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Consequently, the elevated levels of free radicals can damage cellular structures, resulting in the accumulation of cytotoxic substances and ultimately leading to the death of substantia nigra cells, thereby triggering the onset of PD ( 2.3.3 Neurological inflammation loop Neuroinflammation is a significant indicator of PD and plays a pivotal role in its pathogenesis and progression ( Studies have demonstrated that the abnormal aggregation of α-syn is a significant trigger of neuroinflammation in PD (Park et al., 2021)

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Elektronenakzeptor und hält durch seine Anwesenheit den Elektronenfluß im Stoffwechsel einer Zelle aufrecht.Oxygen is the terminal hydrogen or electron acceptor in the metabolic process and its presence maintains the flow of electrons in the metabolism of a cell