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In the 13-week gavage study in B6C3F 1 mice, described in section 7.2 (NTP, 1983a), there were increases in methaemoglobin and reticulocytes in all treated groups, most evident at the high dose (300 mg/kg of body weight per day), with decreases in haemoglobin, haematocrit and red blood cells at 150 and 300 mg/kg of body weight per day
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