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Medications and Glucose-6-Phosphate Dehydrogenase... : Drug Safety

Following 6 wk of ethanol administration, GCLM knockout mice were resistant to alcohol-induced steatosis and exhibited beneficial metabolic and stress responses to chronic ethanol consumption

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While the coming years will throw further light on these issues, it is our view that the well-known effects of environmental factors on ascorbate and glutathione, whether mediated via ROS or other factors, mark them out as central compounds that influence signaling intensity through pathways mediated by other factors such as recognized phytohormones