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Although early NAC treatment is beneficial in limiting the injury, continuous NAC treatment well beyond the injury phase can delay regeneration [72] mainly through impairment of mitochondrial biogenesis, an adaptive response whose role is to maintain or restore homeostasis following mitochondrial dysfunction [71]
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Deoxyribonucleic acid methylation DNA methylation is a highly prominent epigenetic modification that occurs on Cytosine-phosphate-Guanine (CpG) dinucleotides and affects approximately 70% of cytosine bases
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