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These aging hallmarks include instability of the genome, shortening of telomeres, changes in epigenetic regulation, impairment of protein homeostasis, defective macroautophagy, disruptions in nutrient-sensing pathways, mitochondrial dysfunction, cellular senescence, depletion of stem cell reserves, altered cell-to-cell communication, persistent low-grade inflammation, and imbalances in the gut microbiota (dysbiosis) [2]

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During movement, differences in nerve signaling from the right and left ears are interpreted as motion