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Studies have found that ligustrazine can delay the development of DR by inhibiting oxidative stress and retinal ganglion cell apoptosis, down-regulating AGEs content and other ways ( Astragalus polysaccharide alleviated mitochondrial damage and apoptosis induced by metabolic memory by regulating the miR-182/Bcl-2 axis ( 4.3 Advantages and limitations of research Although there are more and more clinical studies on the treatment of PDN with CHM, there is no systematic evaluation and meta-analysis in this direction
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Similar findings of PEITC on apoptosis induction in OVCAR3 cells were also reported [61]
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