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The Effects of Metformin and Simvastatin on the Proliferation and Apoptosis of glioma Cells After 48 h of treatment with low doses of metformin, simvastatin, and their combination, it was observed that the combined treatment had a higher inhibitory effect on the proliferation of U87, LN229, T98G, and U251 glioblastoma cells compared to individual treatments with metformin or simvastatin alone
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Cancer Cell 35 , 721–737.e729 (2019)
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